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NeurobiologyNBIO 101/201. Social and Ethical Issues in the Neurosciences— (Graduate students register for 201.) Influences on public debate and policy of scientific advances in the study of the brain and behavior: theories of brain function; philosophical and scientific approaches; advances in the neurosciences, possible uses in medical therapy, and interventions involving genetic screening, genetic selection, enhancement of neurological functioning, and manipulation of behavior; questions related to medical therapy, social policy, and broader considerations of human nature such as consciousness, free will, personal identity, and moral responsibility. May be taken for 2 units without a research paper. Prerequisite: Neuroscience, Biological Sciences, or Symbolic Systems major or Human Biology core; or consent of instructor. NBIO 206. The Nervous System—Introduction to the structure and function of the nervous system, including neuroanatomy, neurophysiology, and systems neurobiology. Topics include the properties of neurons and the mechanisms and organization underlying higher functions. Framework for general work in neurology, neuropathology, clinical medicine, and for more advanced work in neurobiology. Lecture and lab components must be taken together. NBIO 216. Genetic Analysis of Behavior—(Same as MCP 216.) Advanced seminar. Findings and implications of behavioral genetics as applied to invertebrate and vertebrate model systems. Topics include biological clocks, and sensation and central pattern generators. Relevant genetic techniques and historical perspective. Student presentation. NBIO 218. Neural Basis of Behavior—Advanced seminar. The principles of information processing in the vertebrate central nervous system, and the relationship of functional properties of neural systems with perception and behavior. Emphasis is on the visual and auditory systems. Original papers; student presentations. Prerequisite: 206 or consent of instructor. NBIO 220. Central Mechanisms in Vision-based Cognition—Contemporary visual neuroscience, emphasizing the neural mechanisms underlying primate vision and visually guided behavior. Seven foundational topics in visual neuroscience; current papers concerning each topic. Student presentations. Computer-based demonstration exercises. NBIO 221. Frontiers in Translational Medicine—Small group course for first-year MSTP and MD /PhD. students only. Pathways for combining science and medicine during graduate and postdoctoral training and in one’s career. Practical aspects of translational medicine. Guest lecturers are physician-scientists who have advanced the frontiers of translational medicine, including Drs. Gilbert Chu, Jamie Topper, Irv Weissman, Ching Wang, Linda Giudice, Geoff Duyk, William Mobley, Judy Shizuru, and David Cox. Prerequisite: consent of instructor. NBIO 222. Imaging: Biological Light Microscopy—(Same as BIOSCI 152, MCP 222.) Survey of instruments which use light and other radiation for analysis of cells in biological and medical research. Topics: basic light microscopy through confocal fluorescence and video/digital image processing. Lectures on physical principles; involves partial assembly and extensive use of lab instruments. Lab. Prerequisites: some college physics, Biological Sciences core. NBIO 227. Understanding Techniques in Neuroscience—Techniques commonly used in neuroscience, including molecular/genetic, electrophysiological, and whole brain imaging. Presentations by senior graduate students and examples from the literature. Optional laboratory demonstrations. NBIO 254. Molecular and Cellular Neurobiology—(Same as BIOSCI 154/254.) For advanced undergraduates and graduate students. Cellular and molecular mechanisms in the organization and functions of the nervous system. Topics: wiring of the neuronal circuit, synapse structure and synaptic transmission, signal transduction in the nervous system, sensory systems, molecular basis of behavior including learning and memory, molecular pathogenesis of neurological diseases. Prerequisite for undergraduates: Biological Sciences core or equivalent, or consent of instructors. NBIO 258. Information and Signaling Mechanisms in Neurons and Circuits—(Same as MCP 258.) How synapses, cells, and neural circuits process information relevant to a behaving organism. How phenomena of information processing emerge at several levels of complexity in the nervous system, including sensory transduction in molecular cascades, information transmission through axons and synapses, plasticity and feedback in recurrent circuits, and encoding of sensory stimuli in neural circuits. NBIO 299. Directed Reading in Neurobiology—Prerequisite: consent of instructor. NBIO 300. Professional Development and Integrity in Neuroscience— Required of Neurosciences Ph.D. students every quarter. Develops professional skills in critical assessment and oral presentation of findings from current neuroscience literature in the visual presentation of quantitative data and writing research grants. The role of animals in lab research, fraud in science, the responsibility of authors and reviewers, science in a multicultural environment, and the relationship between student and mentor. Student and faculty presentations and discussions. NBIO 399. Graduate Research—Investigations sponsored by individual faculty members. Prerequisite: consent of instructor. COGNATE COURSES See respective department listings for course descriptions. See degree requirements above or the program’s student services office for applicability of these courses to a major or minor program. PSYCH 204A. Computational Neuroimaging PSYCH 250. High-level Vision
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